Positioned outside of the busy city center, the Sofitel Karnak Luxor is still only a few minutes from the many sites and attractions of the East Bank. It is one of the more convenient accommodations in Luxor due to its proximity to the Luxor and Karnak Temple complex, Luxor Museum, Museum of Mummification, and the open air market as well. A visitor can also book a felucca to take them to the West Bank where attractions like the Valley of the Kings and the Temple of Hatshepsut are located. The Sofitel Karnak Luxor is located along El Zinia Gebly Street and is 3.1 miles from the Luxor International Airport.

Each of the 347 bedrooms in the Sofitel Karnak Luxor is outfitted with satellite TV, high-speed Internet access, climate controls, minibar, a personal safe, and a large private bathroom.

The Sofitel Karnak Luxor provides visitors with many services including an in-house restaurant, 24-hour front desk service, a concierge desk, a lounge with bar service, a currency exchange, meeting and conference rooms, a news stand, a tour desk, a business service center, a swimming pool, airport shuttles, banqueting facilities, a modern fitness room, tennis courts, and free parking on the premises.